Fat-soluble vitamins
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Vitamin A (Retinol)
A fat-soluble vitamin involved in vision, skin and mucous membrane health, and immune function.
Key functions
- Involved in synthesizing rhodopsin, the visual pigment that maintains eyesight in low light.
- Keeps skin and mucous membranes (eyes, respiratory tract, digestive tract) healthy, helping defend against pathogens.
- Supports normal immune cell function, growth, and development.
Possible deficiency symptoms
- Night blindness (reduced vision in low light)
- Dry eyes, corneal damage
- Skin flaking, lowered resistance to infection
Key food sources
Carrots, spinach, pumpkin and other orange/dark-green vegetables (beta-carotene)Animal liverEgg yolkMilk and dairy products
Daily Value (DV): 900 mcg RAE
Overdose cautions
Being fat-soluble, it can accumulate in the body, and long-term excess intake may cause headaches and liver damage. Excess intake during pregnancy has been linked to birth defect risk, so pregnant women should be cautious about supplements.
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Vitamin D (Calciferol)
Helps the body absorb calcium and phosphorus for bone health, and is the one vitamin the skin can synthesize from sunlight.
Key functions
- Promotes calcium and phosphorus absorption in the intestines, keeping bones and teeth strong.
- Also thought to play a role in muscle function and immune regulation.
- The only vitamin the body synthesizes on its own when skin is exposed to sunlight (UVB).
Possible deficiency symptoms
- Children: rickets (soft, bowed bones)
- Adults: osteomalacia, increased osteoporosis risk
- Muscle weakness
Key food sources
Fatty fish such as salmon and mackerelMushrooms (especially sun-dried)Egg yolkSunlight exposure itself (roughly 15-30 minutes a day)
Daily Value (DV): 20 mcg
Overdose cautions
Long-term excess from supplements can cause hypercalcemia (excess blood calcium) and kidney stones. Excess from sun exposure alone has not been reported.
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Vitamin E (Tocopherol)
A powerful antioxidant that protects cell membranes from oxidative damage.
Key functions
- Acts as an antioxidant, protecting the lipids in cell membranes from damage by free radicals.
- Also supports blood vessel health and immune function.
- Works alongside other antioxidant nutrients such as vitamin C and selenium for a stronger combined effect.
Possible deficiency symptoms
- Very rare with a normal diet
- Severe deficiency can cause hemolytic anemia and neurological problems (mostly in people with fat-malabsorption conditions)
Key food sources
Almonds, sunflower seeds and other nuts/seedsVegetable oils (sunflower oil, olive oil, etc.)Spinach, avocado
Daily Value (DV): 15 mg
Overdose cautions
Very high long-term supplement doses can impair blood clotting and raise bleeding risk, so anyone on blood thinners (like warfarin) should consult a doctor before taking high doses.
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Vitamin K (Phylloquinone/Menaquinone)
Helps blood clot normally and also plays a role in bone metabolism.
Key functions
- Essential for synthesizing several clotting-factor proteins needed for normal blood clotting.
- Also activates a bone protein (osteocalcin), linking it to bone health.
- Partly synthesized by gut bacteria as well.
Possible deficiency symptoms
- Tendency for bleeding not to stop easily (newborns, who have low vitamin K reserves, need particular attention)
- Dietary deficiency is rare in healthy adults
Key food sources
Kale, spinach, broccoli and other leafy greensNatto (fermented soybeans)Soybean oil, canola oil
Daily Value (DV): 120 mcg
Overdose cautions
No excess effects have been reported from food alone, but anyone on blood thinners like warfarin should keep their vitamin-K-rich vegetable intake fairly consistent, since sudden large changes can affect the medication's effect.
Water-soluble vitamins
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Vitamin B1 (Thiamine)
Needed for converting carbohydrates into energy and for normal nerve function.
Key functions
- Acts as a coenzyme in the metabolic process that converts carbohydrates (glucose) into energy.
- Involved in maintaining normal nerve cell function.
- Being water-soluble, it isn't stored in large amounts, so steady daily intake is needed.
Possible deficiency symptoms
- Beriberi (leg numbness/swelling, heart failure in severe cases)
- Fatigue, loss of appetite
- In severe cases, neurological problems (Wernicke-Korsakoff syndrome, usually linked to alcohol dependence)
Key food sources
PorkBrown rice, whole grainsLegumes, nuts
Daily Value (DV): 1.2 mg
Overdose cautions
No well-established overdose risk from food or typical supplement use has been reported for this vitamin.
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Vitamin B2 (Riboflavin)
A water-soluble vitamin involved in energy metabolism and skin/mucous membrane health.
Key functions
- Acts as a coenzyme in several metabolic processes that convert carbohydrates, fats, and protein into energy.
- Helps keep skin, eyes, and mucous membrane tissue healthy.
- Sensitive to light, which is why milk and similar products are often stored in light-blocking containers to reduce nutrient loss.
Possible deficiency symptoms
- Cracking at the corners of the mouth (angular cheilitis)
- Glossitis (inflamed tongue)
- Dermatitis, eye discomfort such as sensitivity to light or redness
Key food sources
Milk and dairy productsEggsMushroomsAlmonds and other nuts
Daily Value (DV): 1.3 mg
Overdose cautions
No well-established overdose risk from food or typical supplement use has been reported for this vitamin.
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Niacin (Vitamin B3)
A key energy-metabolism vitamin involved in hundreds of metabolic reactions in the body.
Key functions
- Needed for numerous energy-producing enzyme reactions in carbohydrate, fat, and protein metabolism.
- Also involved in nervous system and digestive function and skin health.
- Partly synthesized in the body from the essential amino acid tryptophan.
Possible deficiency symptoms
- Pellagra (a deficiency disease combining dermatitis, diarrhea, and cognitive decline)
- Loss of appetite, fatigue
Key food sources
Chicken, tuna and other meat/fishPeanuts and other nutsBrown rice, mushrooms
Daily Value (DV): 16 mg NE
Overdose cautions
High-dose supplements (in the nicotinic acid form) commonly cause a "niacin flush" β reddening and burning in the face and upper body β and severe cases can affect liver function.
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Vitamin B5 (Pantothenic acid)
Involved in carbohydrate/fat metabolism and hormone synthesis, and found widely in almost every food.
Key functions
- A core component of coenzyme A, essential for energy metabolism.
- Involved in synthesizing fatty acids, cholesterol, and some hormones and neurotransmitters.
Possible deficiency symptoms
- Deficiency is very rare since it's found in almost all foods
- Fatigue and tingling in the hands/feet have been reported in cases of severe overall malnutrition
Key food sources
EggsMushroomsAvocadoMeat, whole grains
Daily Value (DV): 5 mg
Overdose cautions
No well-established overdose risk from food or typical supplement use has been reported for this vitamin.
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Vitamin B6 (Pyridoxine)
A vitamin involved in protein metabolism and neurotransmitter synthesis.
Key functions
- Acts as a coenzyme needed for amino acid (protein building-block) metabolism.
- Involved in synthesizing neurotransmitters such as serotonin and dopamine.
- Also needed for synthesizing hemoglobin in red blood cells.
Possible deficiency symptoms
- Anemia
- Dermatitis, cracking at the corners of the mouth
- Peripheral nerve problems (tingling in hands/feet)
Key food sources
Chicken breast and other lean meatsBananasPotatoesBrown rice, whole grains
Daily Value (DV): 1.7 mg
Overdose cautions
Very high long-term supplement doses have been reported to cause peripheral neuropathy (tingling, numbness), so while ordinary food intake isn't a concern, high-dose supplements should be used cautiously.
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Biotin (Vitamin B7)
Involved in fat and carbohydrate metabolism, and well known for its association with hair and skin health.
Key functions
- Acts as a coenzyme in several metabolic processes, including fatty acid synthesis and glucose production.
- Associated with hair, skin, and nail health, which is why it's a common supplement ingredient for those purposes.
Possible deficiency symptoms
- Deficiency is generally rare
- Eating large amounts of raw egg white over a long period can cause deficiency, since a protein in raw egg white (avidin) blocks biotin absorption (hair loss, skin rash, etc.)
Key food sources
Egg yolk (cooked)Nuts, legumesSweet potatoes
Daily Value (DV): 30 mcg
Overdose cautions
No well-established overdose risk from food or typical supplement use has been reported for this vitamin.
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Folate (Vitamin B9)
Essential for DNA synthesis and cell division, and particularly important for fetal development in early pregnancy.
Key functions
- Especially important for DNA/RNA synthesis and cell division in fast-dividing tissue such as blood and fetal tissue.
- Involved in red blood cell production; deficiency can cause anemia.
- Essential for the formation of the fetal neural tube (the origin of the brain and spinal cord) in early pregnancy.
Possible deficiency symptoms
- Megaloblastic anemia (abnormally large red blood cells)
- Deficiency during pregnancy raises the risk of neural tube defects (such as spina bifida) in the baby
Key food sources
Spinach, broccoli and other leafy greensLegumesAsparagusLiver
Daily Value (DV): 400 mcg DFE
Overdose cautions
No well-established overdose risk from food or typical supplement use has been reported for this vitamin.
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Vitamin B12 (Cobalamin)
Essential for red blood cell production and nervous system function, and naturally found only in animal foods.
Key functions
- Works with folate in red blood cell production and DNA synthesis.
- Needed to maintain the myelin sheath that insulates nerve cells.
- Not naturally present in plant foods, so vegetarians and vegans need a deliberate intake plan.
Possible deficiency symptoms
- Pernicious anemia (megaloblastic anemia)
- Peripheral nerve problems like tingling in the hands/feet, and cognitive decline in severe cases
- Strict vegans face a higher deficiency risk and are generally advised to supplement
Key food sources
Meat, fish, shellfishEggsMilk and dairy products
Daily Value (DV): 2.4 mcg
Overdose cautions
No well-established overdose risk from food or typical supplement use has been reported for this vitamin.
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Vitamin C (Ascorbic acid)
A powerful antioxidant that's essential for collagen synthesis and also helps iron absorption.
Key functions
- An essential cofactor for synthesizing the collagen that makes up skin, blood vessels, and bone.
- Acts as an antioxidant, protecting cells from damage by free radicals.
- Improves absorption of plant-based iron (non-heme iron).
- Also supports normal immune cell function.
Possible deficiency symptoms
- Scurvy (bleeding gums, slow wound healing, fatigue) β rare today, but can occur with extreme, restrictive diets or malnutrition
Key food sources
Kiwi, strawberries, citrus fruitBell peppers, broccoli and other vegetablesPotatoes
Daily Value (DV): 90 mg
Overdose cautions
Being water-soluble, excess is mostly excreted in urine, but sustained high-dose intake above roughly 2,000 mg/day can raise the risk of digestive upset (diarrhea, cramping) and kidney stones.