Two different routes depending on who you are
A US citizen or resident with a US bank account and Social Security number can buy directly from the government at TreasuryDirect.gov, with no broker and no secondary-market trading. Everyone else -- including US investors who want to sell before maturity -- typically goes through a brokerage account instead, where a wider range of existing issues is available but you may pay a trading spread or commission.
How the interest is generally taxed
In the US, Treasury interest is subject to federal income tax but is generally exempt from state and local income tax, which is one advantage over comparable state or corporate bonds for a US resident. Investors outside the US are taxed under their own country's rules for foreign-sourced interest income, which can differ significantly from the US treatment described above. This page explains general principles only, not tax advice for your specific situation -- tax rules change and vary by country, so confirm current rules or consult a tax professional before investing.
Frequently Asked Questions
Can you buy US Treasuries with a small amount of money?
Through TreasuryDirect, the minimum purchase is as low as $100. Through a brokerage account, minimums and whether fractional purchases are supported vary by broker, so check the specific platform you plan to use.
What does it actually mean that a bond's price and its yield move in opposite directions?
When market interest rates rise, newly issued bonds offer a higher coupon, which makes existing bonds with a lower fixed coupon less attractive at their original price -- so their market price falls to compensate, and vice versa when rates fall. This relationship affects anyone selling a Treasury before maturity, though it does not affect an investor who holds to maturity and receives face value regardless.